Psychosis
Infant, child = 6 month: 0.55 mg/kg PO q 4-6 h prn, or IM q 6-8 h prn; or 1.1 mg/kg PR q 6-8 h prn. Max IM dose 40 mg/day in child < 5 yr and 75 mg/day in child 5-12 yr.
Adult: 25-75 mg PO qd in 2-4 divided doses. Increase twice/wk by 20-50 mg until symptoms controlled. Most pts respond to 200 mg/day; max 800 mg/day.
Nausea, vomiting
Infant, child = 6 month: 0.55 mg/kg PO q 4-6 prn, or IM q 6-8 h prn, or 1.1 mg/kg PR q 6-8 h prn. Max IM dose 40 mg/day in child < 5 yr and 75 mg/day in child 5-12 yr.
Adult: 10-25 mg PO or 25 mg IM q 4-6 h prn, or 100 mg PR q 6-8 h prn.
Tetanus
Infant, child = 6 month: 0.55 mg/kg IM or IV q 6-8 h. For child < 22.7kg, max 40 mg/day; for child 22.7-45.5 kg, max 75 mg/day, except in severe cases.
Adult: 25-50 mg IM or IV tid or qid.
Surgery
Infant, child = 6 month: Preoperative, 0.55 mg/kg PO 2-3 h before surgery or IM 1-2 h before surgery; during surgery, 0.275 mg/kg IM, repeat in 30 min prn, or 1-mg IV q 2 min up to 0.275 mg/kg; repeat IV regimen in 30 min prn; postoperative, 0.55 mg/kg PO or IM q 4-6 h (oral dose) or q h IM prn, if hypotension doesnt occur.
Adult: Preoperative, 25-50 mg PO 2-3 h before surgery or 12.5-25 mg IM 1-2 h before surgery; during surgery, 12.5 mg IM repeated in 30 min prn, or 2-mg IV q 2 min to max 25 mg; postoperative, 10-25 mg PO q 4-6 h or 12.5-25 mg IM repeated in 1 h prn. |